Robust, scalable, and informative clustering for diverse biological networks C Gaiteri, DR Connell, FA Sultan, A Iatrou, B Ng, BK Szymanski, A Zhang, ... Genome Biology 24 (1), 1-27, 2023 | | 2023 |
Benchmarking of deep neural networks for predicting personal gene expression from DNA sequence highlights shortcomings A Sasse, B Ng, AE Spiro, S Tasaki, DA Bennett, C Gaiteri, PL De Jager, ... Nature Genetics, 1-5, 2023 | 5 | 2023 |
The molecular genetic landscape of human brain size variation J Seidlitz, TT Mallard, JW Vogel, YH Lee, V Warrier, G Ball, O Hansson, ... Cell Reports 42 (11), 2023 | 1 | 2023 |
Dissecting the human leptomeninges at single-cell resolution NA Kearns, A Iatrou, DJ Flood, S De Tissera, ZM Mullaney, J Xu, C Gaiteri, ... Nature Communications 14 (1), 7036, 2023 | 3 | 2023 |
Network Analytics Enabled by Generating a Pool of Network Variants from Noisy Data A Mandviwalla, A Elsisy, MS Atique, K Kuzmin, C Gaiteri, BK Szymanski Entropy 25 (8), 1118, 2023 | | 2023 |
Aging the brain: multi-region methylation principal component based clock in the context of Alzheimer’s disease KL Thrush, DA Bennett, C Gaiteri, S Horvath, CH van Dyck, ... Aging (Albany NY) 14 (14), 5641, 2022 | 13 | 2022 |
Inferring protein expression changes from mRNA in Alzheimer’s dementia using deep neural networks S Tasaki, J Xu, DR Avey, L Johnson, VA Petyuk, RJ Dawe, DA Bennett, ... Nature Communications 13 (1), 1-15, 2022 | 33 | 2022 |
Large-scale deep multi-layer analysis of Alzheimer’s disease brain reveals strong proteomic disease-related changes not observed at the RNA level ECB Johnson, EK Carter, EB Dammer, DM Duong, ES Gerasimov, Y Liu, ... Nature Neuroscience, 1-13, 2022 | 243 | 2022 |
Cascading epigenomic analysis for identifying disease genes from the regulatory landscape of GWAS variants B Ng, W Casazza, NH Kim, C Wang, F Farhadi, S Tasaki, DA Bennett, ... PLoS Genetics 17 (11), e1009918, 2021 | 5 | 2021 |
Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors VN Lagomarsino, RV Pearse II, L Liu, YC Hsieh, MA Fernandez, ... Neuron 109 (21), 3402-3420. e9, 2021 | 81 | 2021 |
A cortical immune network map identifies distinct microglial transcriptional programs associated with β-amyloid and Tau pathologies E Patrick, M Olah, M Taga, HU Klein, J Xu, CC White, D Felsky, S Agrawal, ... Translational psychiatry 11 (1), 1-17, 2021 | 22 | 2021 |
Identifying the molecular systems that influence cognitive resilience to Alzheimer's disease in genetically diverse mice SE Heuer, SM Neuner, N Hadad, KMS O'Connell, RW Williams, VM Philip, ... Learning & Memory 27 (9), 355-371, 2020 | 18 | 2020 |
Deconvolving the contributions of cell-type heterogeneity on cortical gene expression E Patrick, M Taga, A Ergun, B Ng, W Casazza, M Cimpean, C Yung, ... PLOS Computational Biology 16 (8), e1008120, 2020 | 83 | 2020 |
Genetics of gene expression in the aging human brain reveal TDP-43 proteinopathy pathophysiology HS Yang, CC White, HU Klein, L Yu, C Gaiteri, Y Ma, D Felsky, ... Neuron 107 (3), 496-508. e6, 2020 | 34 | 2020 |
Meta-analysis of the Alzheimer’s disease human brain transcriptome and functional dissection in mouse models YW Wan, R Al-Ouran, CG Mangleburg, TM Perumal, TV Lee, K Allison, ... Cell reports 32 (2), 107908, 2020 | 209 | 2020 |
Deep learning decodes the principles of differential gene expression S Tasaki, C Gaiteri, S Mostafavi, Y Wang Nature Machine Intelligence 2 (7), 376-386, 2020 | 37 | 2020 |
Microstructural changes in the brain mediate the association of AK4, IGFBP5, HSPB2, and ITPK1 with cognitive decline N Kim, L Yu, R Dawe, VA Petyuk, C Gaiteri, PL De Jager, JA Schneider, ... Neurobiology of aging 84, 17-25, 2019 | 12 | 2019 |
Quantitative Systems Pharmacology for Neuroscience Drug Discovery and Development: Current Status, Opportunities, and Challenges H Geerts, J Wikswo, PH van der Graaf, JPF Bai, C Gaiteri, D Bennett, ... CPT: pharmacometrics & systems pharmacology, 2019 | 39 | 2019 |
Genetic risk for Alzheimer’s dementia predicts motor deficits through multi-omic systems in older adults S Tasaki, C Gaiteri, VA Petyuk, KD Blizinsky, PL De Jager, AS Buchman, ... Translational psychiatry 9 (1), 1-11, 2019 | 15 | 2019 |
Using Transcriptomic Hidden Variables to Infer Context-Specific Genotype Effects in the Brain B Ng, W Casazza, E Patrick, S Tasaki, G Novakovsky, D Felsky, Y Ma, ... The American Journal of Human Genetics 105 (3), 562-572, 2019 | 10 | 2019 |