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Chris Gaiteri
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Robust, scalable, and informative clustering for diverse biological networks
C Gaiteri, DR Connell, FA Sultan, A Iatrou, B Ng, BK Szymanski, A Zhang, ...
Genome Biology 24 (1), 1-27, 2023
2023
Benchmarking of deep neural networks for predicting personal gene expression from DNA sequence highlights shortcomings
A Sasse, B Ng, AE Spiro, S Tasaki, DA Bennett, C Gaiteri, PL De Jager, ...
Nature Genetics, 1-5, 2023
52023
The molecular genetic landscape of human brain size variation
J Seidlitz, TT Mallard, JW Vogel, YH Lee, V Warrier, G Ball, O Hansson, ...
Cell Reports 42 (11), 2023
12023
Dissecting the human leptomeninges at single-cell resolution
NA Kearns, A Iatrou, DJ Flood, S De Tissera, ZM Mullaney, J Xu, C Gaiteri, ...
Nature Communications 14 (1), 7036, 2023
32023
Network Analytics Enabled by Generating a Pool of Network Variants from Noisy Data
A Mandviwalla, A Elsisy, MS Atique, K Kuzmin, C Gaiteri, BK Szymanski
Entropy 25 (8), 1118, 2023
2023
Aging the brain: multi-region methylation principal component based clock in the context of Alzheimer’s disease
KL Thrush, DA Bennett, C Gaiteri, S Horvath, CH van Dyck, ...
Aging (Albany NY) 14 (14), 5641, 2022
132022
Inferring protein expression changes from mRNA in Alzheimer’s dementia using deep neural networks
S Tasaki, J Xu, DR Avey, L Johnson, VA Petyuk, RJ Dawe, DA Bennett, ...
Nature Communications 13 (1), 1-15, 2022
332022
Large-scale deep multi-layer analysis of Alzheimer’s disease brain reveals strong proteomic disease-related changes not observed at the RNA level
ECB Johnson, EK Carter, EB Dammer, DM Duong, ES Gerasimov, Y Liu, ...
Nature Neuroscience, 1-13, 2022
2432022
Cascading epigenomic analysis for identifying disease genes from the regulatory landscape of GWAS variants
B Ng, W Casazza, NH Kim, C Wang, F Farhadi, S Tasaki, DA Bennett, ...
PLoS Genetics 17 (11), e1009918, 2021
52021
Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors
VN Lagomarsino, RV Pearse II, L Liu, YC Hsieh, MA Fernandez, ...
Neuron 109 (21), 3402-3420. e9, 2021
812021
A cortical immune network map identifies distinct microglial transcriptional programs associated with β-amyloid and Tau pathologies
E Patrick, M Olah, M Taga, HU Klein, J Xu, CC White, D Felsky, S Agrawal, ...
Translational psychiatry 11 (1), 1-17, 2021
222021
Identifying the molecular systems that influence cognitive resilience to Alzheimer's disease in genetically diverse mice
SE Heuer, SM Neuner, N Hadad, KMS O'Connell, RW Williams, VM Philip, ...
Learning & Memory 27 (9), 355-371, 2020
182020
Deconvolving the contributions of cell-type heterogeneity on cortical gene expression
E Patrick, M Taga, A Ergun, B Ng, W Casazza, M Cimpean, C Yung, ...
PLOS Computational Biology 16 (8), e1008120, 2020
832020
Genetics of gene expression in the aging human brain reveal TDP-43 proteinopathy pathophysiology
HS Yang, CC White, HU Klein, L Yu, C Gaiteri, Y Ma, D Felsky, ...
Neuron 107 (3), 496-508. e6, 2020
342020
Meta-analysis of the Alzheimer’s disease human brain transcriptome and functional dissection in mouse models
YW Wan, R Al-Ouran, CG Mangleburg, TM Perumal, TV Lee, K Allison, ...
Cell reports 32 (2), 107908, 2020
2092020
Deep learning decodes the principles of differential gene expression
S Tasaki, C Gaiteri, S Mostafavi, Y Wang
Nature Machine Intelligence 2 (7), 376-386, 2020
372020
Microstructural changes in the brain mediate the association of AK4, IGFBP5, HSPB2, and ITPK1 with cognitive decline
N Kim, L Yu, R Dawe, VA Petyuk, C Gaiteri, PL De Jager, JA Schneider, ...
Neurobiology of aging 84, 17-25, 2019
122019
Quantitative Systems Pharmacology for Neuroscience Drug Discovery and Development: Current Status, Opportunities, and Challenges
H Geerts, J Wikswo, PH van der Graaf, JPF Bai, C Gaiteri, D Bennett, ...
CPT: pharmacometrics & systems pharmacology, 2019
392019
Genetic risk for Alzheimer’s dementia predicts motor deficits through multi-omic systems in older adults
S Tasaki, C Gaiteri, VA Petyuk, KD Blizinsky, PL De Jager, AS Buchman, ...
Translational psychiatry 9 (1), 1-11, 2019
152019
Using Transcriptomic Hidden Variables to Infer Context-Specific Genotype Effects in the Brain
B Ng, W Casazza, E Patrick, S Tasaki, G Novakovsky, D Felsky, Y Ma, ...
The American Journal of Human Genetics 105 (3), 562-572, 2019
102019
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Articles 1–20